1) The notion of something from nothing violates basic assumptions of materialism

a. Materialism based upon cause and effect

Dictionary of Philosophy Anthony Flew, article on "Materialism"

"...the belief that everything that exists is either matter or entirely dependent upon matter for its existence." Center For Theology and the Natural Sciences Contributed by: Dr. Christopher Southgate: God, Humanity and the Cosmos (T&T Clark, 1999) http://www.ctns.org/Information/information.html Is the Big Bang a Moment of Creation?(this source is already linked above)

"...Beyond the Christian community there was even greater unease. One of the fundamental assumptions of modern science is that every physical event can be sufficiently explained solely in terms of preceding physical causes. Quite apart from its possible status as the moment of creation, the Big Bang singularity is an offence to this basic assumption. Thus some philosophers of science have opposed the very idea of the Big Bang as irrational and untestable."

b) Something from nothing contradicts materialism

Science and The Modern World, Alfred North Whitehead.
NY: free Press, 1925, (1953) p.76

"We are content with superficial orderings form diverse arbitrary starting points. ... science which is employed in their development [modern thought] is based upon a philosophy which asserts that physical causation is supreme, and which disjoins the physical cause from the final end. It is not popular to dwell upon the absolute contradiction here involved."[Whitehead was an atheist]

c) Causality was the basis upon which God was expelled from Modern Science

It was La Place's famous line "I have no need of that Hypothesis" [meaning God] Which turned the scientific world from believing (along with Newton and assuming that order in nature proved design) to unbelief on the principle that we don't' need God to explain the universe because we have independent naturalistic cause and effect. [Numbers, God and Nature]

2) Materialism Undermines Itself

a) Big Bang contradicts causality (see quotation above)

b) QM theory seems to contradict cause/effect relationship.

c) Rejection of final cause

3) Probabilistic Justification for assumption of Cause

We still have a huge justification for assuming causes inductively, since nothing in our experience is ever uncaused. The mere fact that we can't see or find a cause isn't a proof that there isn't one.

4) Therefore, we have probabilistic justification for assuming Final cause

Thus, the basis upon which God was dismissed from scientific thought has been abandoned; the door to consideration of God is open again. The reliance upon naturalistic cause and effect in consideration of ultimate origins is shattered, but this does not make it rational to just assume that the universe popped into existence with no cause. Since we have vast precedent for assuming cause and effect, we should continue to do so. But since naturalistic cause and effect seems unnecessary at the cosmic level, we should consider the probability of an ultimate necessary final cause.